Bioinformatics and Genomics
Using advanced omics technologies to explore the complex biology of cancers.
Using advanced omics technologies to explore the complex biology of cancers.
We look at cancers at whole tumour, spatial and single-cell levels. 网络彩票APP下载_澳客彩票网-官方游戏, integrated approaches include genomic, transcriptomic and epigenomic sequencing technologies. These techniques allow us to discover new therapeutic targets and biomarkers.
Central to our genomics research is our expertise in computational biology and bioinformatics. 网络彩票APP下载_澳客彩票网-官方游戏, computational biologists and bioinformaticians develop and apply advanced computational tools to analyse large biological and clinical datasets from our omics studies.
We aim to unravel the genetic drivers of tumorigenesis and cancer progression, making use of comprehensive DNA sequencing techniques including:
We employ RNA sequencing approaches such as:
These approaches allow us to interpret gene expression profiles and identify dysregulated pathways critical to cancer. To understand the epigenetic regulation of cancer pathways, we use methods such as:
网络彩票APP下载_澳客彩票网-官方游戏, research has a particular focus on Chronic Lymphocytic Leukaemia and Splenic Marginal Zone Lymphoma. 网络彩票APP下载_澳客彩票网-官方游戏, research also extends beyond B cell cancers to include ongoing collaborations with groups investigating sarcomas and other solid tumours.