View all research projects
Research project

TCR ligand structures

Project overview

Structural characterisation of CD1 reactive T cell receptors including gamma delta and iNKT TCRs through protein crystallography

Staff

Lead researcher

Dr Salah Mansour PhD

Associate Professor

Research interests

  • Unconventioanl T cells in health and disease?
  • CD1 group 1 restricted T cell immunity??
  • Structural and molecular mechainsms of CD1 lipid antigen presentation?
Connect with Salah

Email: S.Mansour@soton.ac.uk

Other researchers

Professor Ivo Tews

Professor

Research interests

  • Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in?the large PLP syntase complexEdit
  • Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
  • Cancer immunology: together with Cancer Immunology at 网络彩票APP下载_澳客彩票网-官方游戏, we use a structure based apporach in developing novel cancer therapie
Connect with Ivo

Email: Ivo.Tews@soton.ac.uk

Collaborating research institutes, centres and groups

Molecular and Precision Biosciences

We research how molecular machinery governs cellular life, developing tools to tackle diseases caused when these molecular operations are disrupted.

Research outputs